Clinical Reference · Updated 2026-05-08

SELECT Trial Results

SELECT (NEJM 2023, PMID 37952131): 20% MACE reduction in non-diabetic adults with overweight/obesity + established CVD. Led to Wegovy's 2024 FDA expansion for CV risk reduction.

Clinical referencePubMed-linkedUpdated 2026-05-08
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Editorial team
Dr. Sam Saberian · Lead Medical Researcher
Reviewed by Julliana Edwards (Editor) · Last updated 2026-05-08

Overview

SELECT (NEJM 2023, PMID 37952131): 20% MACE reduction in non-diabetic adults with overweight/obesity + established CVD. Led to Wegovy's 2024 FDA expansion for CV risk reduction.

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